Tag Archives: Tiroidite di hashimoto

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Thyroid

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The thyroid is a small gland that lies in the neck concerning the level of the Adam’s apple and weighs approximately 1 ounce. It produces thyroid hormone and calcitonin. The parathyroid glands are extremely little and lie on the outside portion from the thyroid gland and secrete parathyroid hormone. We’ll be focusing on thyroid hormone.

The thyroid gland is stimulated to produce thyroid hormone by thyroid-stimulating hormone (TSH) that is created inside the pituitary gland located in the brain. The pituitary is controlled by the hypothalamus within the brain which monitors the amount of circulating thyroid hormone. Iodine need to enter the thyroid gland by means of a transport method which is repaired with all the intake of vitamin C. There is certainly typically about 20-30 mg of iodine within the body and 75 percent of it is stored within the thyroid. Additionally to iodine, magnesium, zinc, copper, and vitamins B2, B3, and B6 are necessary for thyroid hormone production.

The thyroid gland produces two thyroid hormones: T4 (thyroxine) and T3 (triiodothyronine). Ninety-five percent of thyroid hormone produced is T4 and five percent is T3. T3 is the active form of thyroid hormone which is produced as a result of one iodine being cleaved from T4. T4 is inactive so the majority of thyroid hormone made is actually inactive. The numbers “3” and “4” indicate the number of iodines. This can be key in understanding optimal thyroid function. Each T4 and T3 are bound to proteins inside the blood till they attain your cells and turn out to be unbound to function their magic on metabolism.

The majority of the T4 is converted into T3 inside the liver. Roughly sixty percent from the T4 is converted into T3, twenty percent is converted into an inactive form of thyroid hormone identified as reverse T3 (irreversible), as well as the remaining twenty % is converted into T3S (T3 sulfate) and T3AC (triiodothyroacetic acid).

Reverse T3 could be problematic; despite the fact that it’s inactive, it’ll nonetheless bind to T3 receptors and block T3 from binding and working its magic on metabolism. Too significantly or also little cortisol that’s made by the adrenal glands will improve circulating levels of reverse T3. This mechanism is as a result of suppressed liver detoxification and clearance of reverse T3 from excess cortisol production. Stress can not only result in signs of hypothyroidism nevertheless it will also impair the liver’s capability to detoxify. Cortisol will also suppress TSH production resulting in low thyroid function. Immune method activation, high adrenaline, excess free of charge radicals, aging, fasting, tension, prolonged illness, and diabetes may also drive the inactivation of T3 to reverse T3.

T3 and reverse T3 may also be inactivated by conversion into a hormone known as T2. Elevated insulin levels due to a diet program high in refined carbohydrates will also increase reverse T3 levels. Toxic metals such as mercury, cadmium and lead will also improve reverse T3 production. T3S and T3AC are inactive till they may be catalyzed by an enzyme in the GI tract recognized as sulfatase. This enzyme is dependent on healthful gut bacteria. We’ll discuss in a later chapter the significance of a healthful digestive tract since it relates to twenty % of active thyroid hormone.

Thyroid hormone’s principal part would be to handle metabolism (energy production) inside the cell. Our cells include tiny factories known as mitochondria that generate power from fat, sugar and protein. Thyroid hormone controls the function in the mitochondria which determines how much energy is made. Symptoms of low thyroid function are connected to a reduce in power production which includes:

Fatigue
Weight gain/inability to lose weight
Constipation
Dry/itchy skin
Dry brittle hair and nails
Depression
Headaches
Overly sensitive to cold
Cold/numb hands and feet
Muscle cramps
Depressed immune system-can’t recover from infections
Slow wound healing
Unrefreshing sleep
Digestive difficulties due to low stomach acid
Hair falls out
Water retention
Lateral third of eyebrow thinning
TSH

Standard medicine relies mainly around the TSH or thyroid-stimulating hormone blood test to measure thyroid function. TSH just isn’t a thyroid hormone. TSH is made by the pituitary depending on how much thyroid hormone is circulating in the bloodstream. As thyroid hormone levels drop, TSH production will improve to stimulate the thyroid to make much more hormone. If thyroid hormone increases, then TSH production will reduce because the thyroid is making lots of hormone. The TSH alone isn’t sufficient to assess thyroid function because it does not take into consideration the conversion of thyroid hormone into its active type which happens in the liver, kidneys and lungs. The TSH test also doesn’t take into account thyroid hormone receptor resistance. Thyroid hormone receptors can turn out to be resistant to thyroid hormone because of thyroid-disrupting chemical exposure top to regular blood tests but improvement of low thyroid symptoms. Cortisol made throughout anxiety by the adrenal gland can also inhibit TSH production additional throwing off the accuracy in the test. In the event the TSH is elevated, the traditional physician will prescribe synthetic T4 and this can generally minimize TSH into the “normal” variety. This method will not take into account peripheral thyroid hormone conversion or receptor binding. In the event the physique is compromised in its ability to activate thyroid hormone into T3, then taking T4 will result within a failure of treatment. In the event the adrenal glands are out of balance, then probably thyroid hormone function will also be out of balance. Furthermore, if thyroid hormone receptors are desensitized, this approach will fail also.

You are going to find that most medical physicians usually do not spend much time reading the peer-reviewed health-related literature which offers us with useful data on TSH levels. A great study was published by Obal and Krueger (2001)on sleep deprivation and thyroid hormone production. The researchers concluded: “When sleep deprivation is maintained for weeks, the plasma concentrations of T4 and specifically T3 decline but TSH remains normal.”6 Do physicians ask you about your sleep patterns? Possibly this could possibly be the purpose for the abnormal TSH. I have seen many individuals who also suffer from insomnia and sleep problems and present with low thyroid symptoms and abnormal TSH levels. Does this imply they must have thyroid hormone dumped into their bodies? Sadly, this occurs to many people. I often take into account every patient’s sleep pattern and appropriate it as a part of our therapy plan. Numerous instances, sleep patterns are abnormal as a result of blood sugar and adrenal gland imbalances. Bear in mind, you’re not a lab test but a stunning, complicated getting exactly where everything is connected as a single.

Testing & Diagnosis

Blood tests alone cannot always adequately diagnose thyroid hormone imbalance. It’s estimated that about forty % of the U.S. population suffers from some kind of thyroid imbalance as opposed to the current traditional figure of ten percent. This really is as a result of the inadequacies of the TSH test. In addition to blood testing, I review a thorough case history and a variety of detailed health questionnaires and also perform a comprehensive physical examination for clues to thyroid hormone imbalance. Basal physique temperature testing is used by many practitioners to evaluate thyroid function but this does not solely indicate a thyroid imbalance. There are many other factors that can result in a low basal physique temperature such as adrenal fatigue, leaky gut, impaired liver detoxification and malnutrition. I use the basal body temperature simply as one a lot more diagnostic tool to evaluate the overall picture of a patient. Another sign that may indicate low thyroid function is thinning from the lateral one-third of the eyebrow.

The following thyroid tests can provide much more information about your thyroid. Use this as a guide when you get the results of your blood tests:

TSH (Thyrotropin) – Thyroid-stimulating hormone is made by the pituitary to stimulate the thyroid to create hormone. The ideal range is 1.8-3.0. Standard medicine uses a significantly broader range of 0.5-5.5. This variety misses numerous hypothyroid patients such as those with a TSH between three.0-5.5.

Total Thyroxine (T4) – This test measures the level of T4 (thyroxine) which is each bound to protein and unbound.

Free of charge Thyroxine Index – This is calculated by multiplying the TT4 by the T3 uptake. The outcome gives you the quantity of unbound T4 or Free of charge T4.

Totally free Thyroxine (Totally free T4) – This measures the level of unbound or free T4 which is the most active type. Free T4 isn’t affected by medications or other factors that affect protein bound thyroxine (TT4).

T3 Uptake – A measurement in the level of available binding sites for totally free T3 on thyroxine-binding proteins. Elevated testosterone will minimize the amount of binding sites and trigger a low T4 and high T3 uptake. Excess estrogen from hormone replacement or birth control pills will boost binding sites and can cause high T4 and low T3 uptake.

Totally free Triiodothyronine (Free of charge T3) – This can be a measure of totally free T3 levels or unbound T3. This really is the best test if your natural physician wants to see the quantity of available active thyroid hormone inside the bloodstream.

Reverse T3 (rT3) – This can be a measurement in the quantity of T3 that has been inactivated.

Thyroid Antibodies – Thyroid peroxidase, thyroid-stimulating immunoglobulin and antithyroglobulin elevations indicate autoimmune thyroid disease such as Tiroidite di hashimoto‘s or Graves’ disease. Thyroglobulin and calcitonin are mostly used within the diagnosis of a lot more serious thyroid diseases such as cancer.

Prescription Medications

Prescription medications do not take into account underlying physiological imbalances and may lead to dependence on the medication. The following drugs are prescribed by physicians to treat the thyroid:

Synthroid – Synthetic thyroxine (T4). Synthroid will be the most popular prescription drug for hypothyroidism. Synthroid is in the top five most commonly prescribed drugs in the US. Synthroid may be converted incorrectly into inactive reverse T3 resulting in no symptom improvement. Synthroid depletes calcium for bones and may not provide improvement for patients who have compromised conversion pathways of T4 into T3 or any of the other imbalances described in this book.
Levoxyl – Synthetic thyroxine (T4).
Levothroid – Synthetic thyroxine (T4).
Levothyroxine – Synthetic thyroxine (T4).
Thyrolar – Synthetic T4 and T3.
Cytomel – Synthetic T3. Numerous side effects such as hyperthyroid symptoms.

Armour Thyroid, Nature Thyroid, Westhroid – Natural thyroid hormone from desiccated pig thyroid tissue. Contains roughly 38 micrograms/grain of T4 and 9 micrograms of T3/grain also as other cofactors for thyroid hormone production. Nature Thyroid is a better choice than Armour simply because it doesn’t contain corn and other binders.

Numerous alternative-minded health-related doctors prescribe Armour and other natural desiccated pig thyroid tissue. This is a better option in some cases than merely prescribing synthetic T4 (Synthroid) because these natural agents also include T3. The problem with Armour is that it contains corn and other fillers which could be a problem for those with specific sensitivities. Nature Thyroid is the best choice simply because it does not contain corn or fillers. But the author does not agree with this remedy method since even though it is a better option, it nonetheless doesn’t take into account the underlying causes of why the thyroid is out of balance in the first place. These natural prescriptions nevertheless only replace thyroid hormone and require dependence around the doctor for continued prescriptions and office visits. I have observed numerous, many patients who are on such natural prescriptions who nonetheless have several symptoms and have been taking the prescription for a long period of time. Even if someone responds to a prescription such as Armour thyroid, she should be rigorously evaluated for underlying physiological imbalances.

Another issue with such therapy methods is suppression of hypothalamic-pituitary-thyroid feedback mechanisms. Whenever you take a hormone which is produced inside the physique, this tells the brain that it no longer needs to stimulate hormone production simply because it’s constantly becoming ingested. When male bodybuilders take testosterone, their testicles shrink simply because there is certainly no longer a need for them to make testosterone. Taking thyroid hormone for long periods of time will suppress natural production which may or may not return after discontinuing the medication. It is strongly encouraged that you do every thing possible to normalize thyroid function before going on medication of any kind. Americans typically want a quick fix, a magic pill that will instantly give relief. A lot of people get this instant relief from medication but the long-term effects of dependency and suppression of natural hormone production may not be worth it. Patients who have had their thyroid removed or partially removed may require prescription thyroid hormone. When the gland just isn’t present then thyroid hormone must be replaced. In this case, prescriptions such as Armour and Nature Thyroid are the better choice.

Conversion of T4 into T3

T3 is much much more active than T4 and is responsible for most of the actions of thyroid hormone around the cell. Some individuals cannot convert T4 into T3 as efficiently as others. Furthermore, there are many factors that could be inhibiting this process.

Selenium, antioxidants, iron, magnesium, zinc, vitamin A, vitamin B6 and B12 deficiencies can lead to poor conversion. The medications listed above affect thyroid hormone conversion as well as production and receptor binding. As people get older, they shed their capability to convert thyroid hormone which may be because of decreased vitamin and mineral absorption. This really is due to a loss of intestinal barrier function exactly where all of your nutrition is absorbed. This barrier loses its function as we age so supplementation is absolutely necessary. Excess estrogen from xenoestrogens in the environment, birth manage pills and hormone replacement can lead to low thyroid symptoms. Estrogen increases the protein that binds to thyroid hormone leaving excess thyroid hormone bound to protein which can be inactive until it becomes unbound. Cortisol produced by the adrenal gland is a major factor in converting thyroid hormone. Also significantly cortisol can inhibit the activation of thyroid hormone and too tiny cortisol yields the same result. Exhausted adrenals will cause low thyroid symptoms due to the lack of cortisol production. Insulin is a hormone released by the pancreas to handle blood sugar elevations after consumption of carbohydrates and can inhibit hormone conversion as well. Soy products have been shown to inhibit the conversion of thyroid hormone. This only goes for soy products that are non-fermented. Fermented soy products such as miso and tempeh are okay.

Vitamin C has been shown to enhance the conversion of thyroid hormone. Radiation, chemotherapy, growth hormone deficiency, and cigarette smoke have also been shown to minimize thyroid hormone conversion.


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Thyroid Problems

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To be able to prevent a disease from taking place, it really is essential to very first understand it. And the most important factor to know and realize may be the root cause of a illness. What caused this illness within the very first spot? What experiences or circumstances did the person do that in the end led to this illness infecting that person? Once this is understood, it will likely be less difficult to stop that disease from carrying out any harm to the person.

Within the case of thyroid diseases, it is a lot more crucial to know the root cause of these ailments because the symptoms that they show are usually connected with distinct ailments or conditions. Now the causes for thyroid difficulties differ per disease. Some are caused by other thyroid illnesses, some are brought on by treatment or medication, some are as a result of a deficiency or an excess of certain nutrients within the physique and you will find other individuals that are hereditary.

Take Hashimoto’s Illness or Hashimoto’s Thyroiditis. This really is an Ipotiroidismo autoimmune illness wherein your immune program attacks the thyroid gland. The root result in of this disease is unknown, but doctors and scientists identify a number of aspects that might have brought on this disease. The two most common causes for this illness is believed to be a genetic flaw and gender. It is believed that genes play a part within a person creating Hashimoto’s Disease, scientists even though have however to recognize what gene or genes are prone to this disease. Gender make-up is also believed to play a part as ladies are more susceptible to create this illness than men (pregnancy is also believed to become a major factor for developing this disease). Other causes are believed to become iodine deficiency and radiation exposure.

Just like Hashimoto’s Disease, the underlying cause of Graves’ Illness are also unknown. It is believed that genes and gender play a major part in causing Graves’ Illness. Women also have greater danger in creating this disease than males, especially pregnant females. Other factors believed to trigger Graves’ Illness are stress and infection. Stress and infection might trigger the onset from the disease to individuals who are prone to getting them but you’ll find no research that straight hyperlink them for the trigger of the disease.

It’s essential to take note of this two diseases as they are the two typical causes of most, if not all, of thyroid difficulties.

One thyroid issue that may be attributed to these two disease is Thyroiditis. Thyroiditis is the inflammation from the thyroid gland. Probably the most common trigger for inflammation in the thyroid is autoimmune disease. Within this illness, the immune system malfunctions, causing the antibodies to attack the thyroid gland. Virus and bacteria can also cause Thyroiditis as particular bacteria and virus attack the thyroid gland straight. Particular drugs including interferon and amiodarone also cause Thyroiditis because they possess the tendency to damage thyroid cells.

Like thyroiditis, Hypothyroidism can also be attributable to autoimmune illness, particularly the Hashimoto’s Disease. The harm that the disease causes for the thyroid gland impacts the ability in the gland to generate hormones. Autoimmune disease is just one of many causes for Hypothyroidism, you’ll find other aspects that result in this circumstances and they are:

Treatment for Hyperthyroidism – Getting an overactive thyroid is usually treated with radioactive iodine or anti-thyroid medicines. You will find instances nonetheless exactly where the remedy for hyperthyroidism caused permanent hypothyroidism.

Radiation Therapy – Treating cancer with radiation inside the neck and head can at times impact your thyroid and trigger hypothyroidism

Thyroid Surgery – Removing parts or all of your thyroid gland will impact hormone production. It’s going to typically demand you to take thyroid hormone drugs.

Drugs – Particular drugs may cause hypothyroidism like lithium. It’s important to seek advice from together with your doctor on the effects in the drugs you take.

Other achievable causes of hypothyroidism are — congenital disease, pituitary disorder, pregnancy and iodine deficiency
An additional condition that’s typically brought on by autoimmune illness, especially Graves’ Illness is Hyperthyroidism. Antibodies that attach itself towards the thyroid gland causes it to generate more hormones. Apart from Graves’ Illness, other causes of Hyperthyroidism are:

Toxic Nodular Goiter – A solitary hot nodule found within the thyroid can occasionally trigger the thyroid to produce more hormones than usual.

Thyroiditis – Inflammation from the thyroid gland can cause it to create excess hormones which are normally stored in the gland. Subacute thyroiditis and postparum thyroiditis would be the most common thyroidits that causes Hyperthyroidism.

Medication – Taking thyroid hormone drugs in excess can also result in Hyperthyroidism. It’s essential to always seek the advice of along with your doctor before taking any medication to acquire the proper dosage

Abnormal secretion of TSH – a problem with all the pituitary gland might create an abnormally high secretion of thyroid stimulating hormone (TSH). This may result in signaling the thyroid gland to create much more hormones.
Thyroid Nodules is also a thyroid difficulty which is brought on by Hashimoto’s Illness however the principal culprit for Thyroid Nodules is Iodine deficiency. A severe lack of iodine inside your diet plan can cause thyroid nodules. Iodine is needed to generate the hormone thyroxine. Other causes of Thyroid Nodules are:

Overgrowth of normal Thyroid Tissue – This can be also called Thyroid Adenoma. It’s unclear to why this occurs but the thyroid adenoma can occasionally trigger the thyroid to generate hormones outside the pituitary glands regulations thus producing more thyroid hormones than needed.

Thyroid Cyst – These fluid-filled cavities (cyst) outcomes from degenerating thyroid adenomas. They may be generally benign but can at times include malignant strong elements.

Thyroid Cancer – The possibilities of nodules becoming malignant are uncommon. The danger becomes larger though depending on you and your family’s medical history.

Broken Pituitary Gland – Difficulties with all the pituitary gland also can result in Thyroid Nodules.
Goiter is an additional thyroid difficulty which is either attributable to Graves Disease or Hashimoto’s Illness. The enlargement from the gland may be caused by either a lot of hormone or lack of it. Other causes of goiter are as follows:

Iodine Deficiency – Lack of iodine inside the body is actually the key trigger of Goiter. It is very essential in the production of thyroid hormones. Goiter is triggered when the thyroid enlarges in an effort to get more iodine.

Multinodular Goiter – Strong or fluid-filled lumps called nodules develop in both sides in the thyroid. This leads to more than enlargement from the gland.

Solitary Thyroid Nodules – A single nodule develops in 1 side in the thyroid gland. This also causes enlargement.

Thyroid Cancer – This is a much less common lump that develops in our thyroid gland. The cancer lump may also outcome inside the formation of Goiter.

Thyroiditis – Inflammation from the thyroid gland may also trigger Goiter due to the swelling.
Pregnancy – A hormone produced in the course of the initial tri-mester of pregnance (human chorionic gonadotrophin or HCG) may cause Goiter. The gland blunders HCG for thyroid stimulating hormone (TSH) and enlarges in response to it.
As you can see, it really is still unclear as for the real result in of thyroid issues. All problems have a number of elements to consider, but the real root trigger have however to become identified (save for iodine deficiency). You might notice that a thyroid problem can bring about a number of much more thyroid difficulties. It is crucial to often have check-up along with your doctor, specifically in the event you really feel something different or abnormal together with your thyroid gland.

Taking care from the problem early will aid lessen the issue and can save you cash.


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Thyroid

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The thyroid is really a little gland that lies within the neck concerning the level of the Adam’s apple and weighs roughly a single ounce. It produces thyroid hormone and calcitonin. The parathyroid glands are extremely small and lie around the outside portion of the thyroid gland and secrete parathyroid hormone. We are going to be focusing on thyroid hormone.

The thyroid gland is stimulated to produce thyroid hormone by thyroid-stimulating hormone (TSH) that is produced within the pituitary gland located within the brain. The pituitary is controlled by the hypothalamus inside the brain which monitors the amount of circulating thyroid hormone. Iodine must enter the thyroid gland via a transport system that is repaired with the intake of vitamin C. There is certainly usually about 20-30 mg of iodine in the physique and 75 percent of it’s stored within the thyroid. Additionally to iodine, magnesium, zinc, copper, and vitamins B2, B3, and B6 are needed for thyroid hormone production.

The thyroid gland produces two thyroid hormones: T4 (thyroxine) and T3 (triiodothyronine). Ninety-five percent of thyroid hormone made is T4 and five % is T3. T3 is the active form of thyroid hormone which can be made as a result of 1 iodine being cleaved from T4. T4 is inactive so the majority of thyroid hormone created is really inactive. The numbers “3” and “4” indicate the number of iodines. This is important in understanding optimal thyroid function. Each T4 and T3 are bound to proteins inside the blood till they reach your cells and grow to be unbound to work their magic on metabolism.

Most of the T4 is converted into T3 in the liver. Roughly sixty % of the T4 is converted into T3, twenty percent is converted into an inactive form of thyroid hormone known as reverse T3 (irreversible), and the remaining twenty percent is converted into T3S (T3 sulfate) and T3AC (triiodothyroacetic acid).

Reverse T3 may be problematic; despite the fact that it’s inactive, it’ll nevertheless bind to T3 receptors and block T3 from binding and functioning its magic on metabolism. Also a lot or as well little cortisol that’s produced by the adrenal glands will boost circulating levels of reverse T3. This mechanism is because of suppressed liver detoxification and clearance of reverse T3 from excess cortisol production. Stress can not merely trigger signs of hypothyroidism however it may also impair the liver’s ability to detoxify. Cortisol may also suppress TSH production resulting in low thyroid function. Immune method activation, high adrenaline, excess free radicals, aging, fasting, anxiety, prolonged illness, and diabetes may also drive the inactivation of T3 to reverse T3.

T3 and reverse T3 also can be inactivated by conversion into a hormone recognized as T2. Elevated insulin levels due to a diet program high in refined carbohydrates will also improve reverse T3 levels. Toxic metals such as mercury, cadmium and lead will also boost reverse T3 production. T3S and T3AC are inactive until they are catalyzed by an enzyme in the GI tract known as sulfatase. This enzyme is dependent on healthful gut bacteria. We will go over within a later chapter the importance of a wholesome digestive tract as it relates to twenty percent of active thyroid hormone.

Thyroid hormone’s main role would be to manage metabolism (energy production) inside the cell. Our cells contain tiny factories called mitochondria that produce power from fat, sugar and protein. Thyroid hormone controls the function from the mitochondria which determines just how much power is produced. Symptoms of low thyroid function are associated to a reduce in power production including:

Fatigue
Weight gain/inability to shed weight
Constipation
Dry/itchy skin
Dry brittle hair and nails
Depression
Headaches
Overly sensitive to cold
Cold/numb hands and feet
Muscle cramps
Depressed immune system-can’t recover from infections
Slow wound healing
Unrefreshing sleep
Digestive problems because of low stomach acid
Hair falls out
Water retention
Lateral third of eyebrow thinning
TSH

Traditional medicine relies primarily on the TSH or thyroid-stimulating hormone blood test to measure thyroid function. TSH isn’t a thyroid hormone. TSH is made by the pituitary according to how much thyroid hormone is circulating inside the bloodstream. As thyroid hormone levels drop, TSH production will increase to stimulate the thyroid to make much more hormone. If thyroid hormone increases, then TSH production will decrease since the thyroid is making plenty of hormone. The TSH alone is not adequate to assess thyroid function since it does not take into consideration the conversion of thyroid hormone into its active kind which happens in the liver, kidneys and lungs. The TSH test also doesn’t take into account thyroid hormone receptor resistance. Thyroid hormone receptors can grow to be resistant to thyroid hormone due to thyroid-disrupting chemical exposure major to typical blood tests but improvement of low thyroid symptoms. Cortisol created during tension by the adrenal gland can also inhibit TSH production further throwing off the accuracy in the test. If the TSH is elevated, the traditional physician will prescribe synthetic T4 and this can usually minimize TSH in to the “normal” variety. This strategy will not take into account peripheral thyroid hormone conversion or receptor binding. When the physique is compromised in its capability to activate thyroid hormone into T3, then taking T4 will outcome within a failure of therapy. If the adrenal glands are out of balance, then probably thyroid hormone function will also be out of balance. In addition, if thyroid hormone receptors are desensitized, this strategy will fail too.

You will find that most medical physicians do not devote a lot time reading the peer-reviewed healthcare literature which provides us with valuable information on TSH levels. An excellent study was published by Obal and Krueger (2001)on sleep deprivation and thyroid hormone production. The researchers concluded: “When sleep deprivation is maintained for weeks, the plasma concentrations of T4 and particularly T3 decline but TSH remains normal.”6 Do physicians ask you about your sleep patterns? Perhaps this might be the reason for Ipotiroidismo gravidanza the abnormal TSH. I’ve seen many sufferers who also suffer from insomnia and sleep problems and present with low thyroid symptoms and abnormal TSH levels. Does this imply they should have thyroid hormone dumped into their bodies? Sadly, this takes place to a lot of people. I always take into account every patient’s sleep pattern and appropriate it as part of our therapy program. Several times, sleep patterns are abnormal as a result of blood sugar and adrenal gland imbalances. Bear in mind, you are not a lab test but a stunning, complex becoming where everything is connected as one.

Testing & Diagnosis

Blood tests alone cannot usually adequately diagnose thyroid hormone imbalance. It’s estimated that about forty percent of the U.S. population suffers from some kind of thyroid imbalance as opposed to the current conventional figure of ten %. This is as a result of the inadequacies from the TSH test. Furthermore to blood testing, I review a thorough case history and a quantity of detailed health questionnaires and also perform a comprehensive physical examination for clues to thyroid hormone imbalance. Basal body temperature testing is used by several practitioners to evaluate thyroid function but this does not solely indicate a thyroid imbalance. There are many other factors that can trigger a low basal physique temperature such as adrenal fatigue, leaky gut, impaired liver detoxification and malnutrition. I use the basal body temperature simply as one a lot more diagnostic tool to evaluate the overall picture of a patient. Another sign that may indicate low thyroid function is thinning in the lateral one-third of the eyebrow.

The following thyroid tests can provide more information about your thyroid. Use this as a guide when you get the results of your blood tests:

TSH (Thyrotropin) – Thyroid-stimulating hormone is made by the pituitary to stimulate the thyroid to create hormone. The ideal range is 1.8-3.0. Traditional medicine uses a much broader variety of 0.5-5.5. This variety misses numerous hypothyroid patients such as those with a TSH between three.0-5.5.

Total Thyroxine (T4) – This test measures the amount of T4 (thyroxine) that is both bound to protein and unbound.

Free of charge Thyroxine Index – This really is calculated by multiplying the TT4 by the T3 uptake. The result gives you the quantity of unbound T4 or Free of charge T4.

Free Thyroxine (Free T4) – This measures the quantity of unbound or totally free T4 which can be the most active type. Free of charge T4 just isn’t affected by medications or other factors that affect protein bound thyroxine (TT4).

T3 Uptake – A measurement of the amount of available binding sites for free of charge T3 on thyroxine-binding proteins. Elevated testosterone will reduce the number of binding sites and trigger a low T4 and high T3 uptake. Excess estrogen from hormone replacement or birth control pills will increase binding sites and can trigger high T4 and low T3 uptake.

Free of charge Triiodothyronine (Free of charge T3) – This really is a measure of totally free T3 levels or unbound T3. This really is the best test if your natural doctor wants to see the quantity of available active thyroid hormone within the bloodstream.

Reverse T3 (rT3) – This can be a measurement in the level of T3 that has been inactivated.

Thyroid Antibodies – Thyroid peroxidase, thyroid-stimulating immunoglobulin and antithyroglobulin elevations indicate autoimmune thyroid disease such as Hashimoto’s or Graves’ disease. Thyroglobulin and calcitonin are mostly used within the diagnosis of much more serious thyroid diseases such as cancer.

Prescription Medications

Prescription medications don’t take into account underlying physiological imbalances and may lead to dependence on the medication. The following drugs are prescribed by physicians to treat the thyroid:

Synthroid – Synthetic thyroxine (T4). Synthroid will be the most popular prescription drug for hypothyroidism. Synthroid is within the top five most commonly prescribed drugs within the US. Synthroid can be converted incorrectly into inactive reverse T3 resulting in no symptom improvement. Synthroid depletes calcium for bones and may not provide improvement for patients who have compromised conversion pathways of T4 into T3 or any from the other imbalances described in this book.
Levoxyl – Synthetic thyroxine (T4).
Levothroid – Synthetic thyroxine (T4).
Levothyroxine – Synthetic thyroxine (T4).
Thyrolar – Synthetic T4 and T3.
Cytomel – Synthetic T3. Many side effects including hyperthyroid symptoms.

Armour Thyroid, Nature Thyroid, Westhroid – Natural thyroid hormone from desiccated pig thyroid tissue. Contains approximately 38 micrograms/grain of T4 and 9 micrograms of T3/grain as well as other cofactors for thyroid hormone production. Nature Thyroid is really a better choice than Armour because it doesn’t include corn and other binders.

Many alternative-minded healthcare doctors prescribe Armour and other natural desiccated pig thyroid tissue. This is a better option in some cases than merely prescribing synthetic T4 (Synthroid) because these natural agents also include T3. The problem with Armour is that it contains corn and other fillers which may be a problem for those with specific sensitivities. Nature Thyroid will be the best choice because it doesn’t contain corn or fillers. But the author doesn’t agree with this treatment method since although it’s a better option, it nevertheless doesn’t take into account the underlying causes of why the thyroid is out of balance in the first place. These natural prescriptions nonetheless only replace thyroid hormone and require dependence on the doctor for continued prescriptions and office visits. I have observed several, numerous individuals who are on such natural prescriptions who still have several symptoms and have been taking the prescription for a long period of time. Even if someone responds to a prescription such as Armour thyroid, she must be rigorously evaluated for underlying physiological imbalances.

Another issue with such treatment methods is suppression of hypothalamic-pituitary-thyroid feedback mechanisms. Whenever you take a hormone that is created within the physique, this tells the brain that it no longer needs to stimulate hormone production simply because it’s constantly getting ingested. When male bodybuilders take testosterone, their testicles shrink because there’s no longer a need for them to create testosterone. Taking thyroid hormone for long periods of time will suppress natural production which may or may not return after discontinuing the medication. It is strongly encouraged that you do every little thing possible to normalize thyroid function before going on medication of any kind. Americans typically want a quick fix, a magic pill that will instantly give relief. Lots of people get this instant relief from medication but the long-term effects of dependency and suppression of natural hormone production may not be worth it. Sufferers who have had their thyroid removed or partially removed may require prescription thyroid hormone. In the event the gland is not present then thyroid hormone need to be replaced. In this case, prescriptions such as Armour and Nature Thyroid are the better choice.

Conversion of T4 into T3

T3 is significantly a lot more active than T4 and is responsible for the majority of the actions of thyroid hormone around the cell. Some folks cannot convert T4 into T3 as efficiently as others. Furthermore, there are several factors that could possibly be inhibiting this process.

Selenium, antioxidants, iron, magnesium, zinc, vitamin A, vitamin B6 and B12 deficiencies can lead to poor conversion. The medications listed above affect thyroid hormone conversion also as production and receptor binding. As people get older, they lose their capability to convert thyroid hormone which may be because of decreased vitamin and mineral absorption. This really is due to a loss of intestinal barrier function exactly where all of your nutrition is absorbed. This barrier loses its function as we age so supplementation is absolutely necessary. Excess estrogen from xenoestrogens in the environment, birth manage pills and hormone replacement can lead to low thyroid symptoms. Estrogen increases the protein that binds to thyroid hormone leaving excess thyroid hormone bound to protein that is inactive until it becomes unbound. Cortisol made by the adrenal gland is a major factor in converting thyroid hormone. As well a lot cortisol can inhibit the activation of thyroid hormone and too little cortisol yields the same result. Exhausted adrenals will result in low thyroid symptoms as a result of the lack of cortisol production. Insulin is actually a hormone released by the pancreas to handle blood sugar elevations after consumption of carbohydrates and can inhibit hormone conversion as well. Soy products have been shown to inhibit the conversion of thyroid hormone. This only goes for soy products that are non-fermented. Fermented soy products such as miso and tempeh are okay.

Vitamin C has been shown to enhance the conversion of thyroid hormone. Radiation, chemotherapy, growth hormone deficiency, and cigarette smoke have also been shown to reduce thyroid hormone conversion.


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Thyroid Problems

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<img src="http://image.baidu.com/search/http:%5C/%5C/n1image.hjfile.cn%5C/qa%5C/2019%5C/02%5C/25%5C/6dd89f3c323439aba237115003854413.jpg" alt="riduca del 27% l’insorgere di sbalzi umorali e sintomi” style=”max-width:400px;float:right;padding:10px 0px 10px 10px;border:0px;”>To become capable to stop a disease from happening, it is important to initial realize it. And the most significant thing to understand and comprehend will be the root cause of a illness. What caused this disease in the very first place? What experiences or circumstances did the particular person do that eventually led to this disease infecting that particular person? Once this is understood, it will be less difficult to prevent that disease from doing any harm towards the individual.

Within the case of thyroid ailments, it really is a lot more crucial to understand the root cause of these illnesses since the symptoms that they show are usually connected with different diseases or situations. Now the causes for thyroid issues differ per illness. Some are brought on by other thyroid diseases, some are attributable to remedy or medication, some are as a result of a deficiency or an excess of specific nutrients in the body and you’ll find other individuals that are hereditary.

Take Hashimoto’s Disease or Hashimoto’s Thyroiditis. This is an autoimmune disease wherein your immune method attacks the thyroid gland. The root trigger of this disease is unknown, but doctors and scientists determine a number of elements that might have caused this illness. The two most typical causes for this disease is believed to become a genetic flaw and gender. It really is believed that genes play a part within a particular person building Hashimoto miglior cura‘s Disease, scientists although have but to determine what gene or genes are prone to this disease. Gender make-up is also believed to play a function as ladies are more susceptible to create this disease than guys (pregnancy is also believed to become a significant element for creating this disease). Other causes are believed to be iodine deficiency and radiation exposure.

Just like Hashimoto’s Disease, the underlying trigger of Graves’ Illness are also unknown. It really is believed that genes and gender play a major part in causing Graves’ Illness. Women also have greater threat in building this disease than men, especially pregnant females. Other aspects believed to cause Graves’ Illness are tension and infection. Anxiety and infection might trigger the onset of the illness to folks who’re prone to getting them but you’ll find no research that straight hyperlink them to the result in in the disease.

It’s crucial to take note of this two illnesses as they’re the two common causes of most, if not all, of thyroid difficulties.

1 thyroid difficulty that can be attributed to these two illness is Thyroiditis. Thyroiditis is the inflammation from the thyroid gland. The most frequent trigger for inflammation within the thyroid is autoimmune illness. In this disease, the immune program malfunctions, causing the antibodies to attack the thyroid gland. Virus and bacteria may also cause Thyroiditis as certain bacteria and virus attack the thyroid gland straight. Specific drugs like interferon and amiodarone also cause Thyroiditis because they possess the tendency to harm thyroid cells.

Like thyroiditis, Hypothyroidism can also be attributable to autoimmune illness, particularly the Hashimoto’s Illness. The damage that the disease causes towards the thyroid gland affects the ability from the gland to produce hormones. Autoimmune disease is just among the causes for Hypothyroidism, you will find other elements that trigger this situations and they are:

Treatment for Hyperthyroidism – Getting an overactive thyroid is usually treated with radioactive iodine or anti-thyroid medicines. You’ll find instances however exactly where the treatment for hyperthyroidism triggered permanent hypothyroidism.

Radiation Remedy – Treating cancer with radiation inside the neck and head can occasionally affect your thyroid and cause hypothyroidism

Thyroid Surgery – Removing components or all of your thyroid gland will impact hormone production. It will generally need you to take thyroid hormone drugs.

Medications – Specific drugs can cause hypothyroidism like lithium. It really is essential to seek advice from together with your medical doctor on the effects in the medicines you take.

Other feasible causes of hypothyroidism are — congenital disease, pituitary disorder, pregnancy and iodine deficiency
Yet another condition that’s typically brought on by autoimmune illness, particularly Graves’ Disease is Hyperthyroidism. Antibodies that attach itself to the thyroid gland causes it to generate more hormones. Aside from Graves’ Disease, other causes of Hyperthyroidism are:

Toxic Nodular Goiter – A solitary hot nodule identified within the thyroid can at times cause the thyroid to create much more hormones than usual.

Thyroiditis – Inflammation from the thyroid gland may cause it to generate excess hormones that are usually stored inside the gland. Subacute thyroiditis and postparum thyroiditis would be the most typical thyroidits that causes Hyperthyroidism.

Medication – Taking thyroid hormone drugs in excess can also trigger Hyperthyroidism. It really is crucial to usually seek advice from together with your doctor just before taking any medication to get the correct dosage

Abnormal secretion of TSH – an issue using the pituitary gland may produce an abnormally high secretion of thyroid stimulating hormone (TSH). This will lead to signaling the thyroid gland to generate a lot more hormones.
Thyroid Nodules can also be a thyroid difficulty that is caused by Hashimoto’s Disease but the primary culprit for Thyroid Nodules is Iodine deficiency. A extreme lack of iodine in your diet plan may cause thyroid nodules. Iodine is necessary to create the hormone thyroxine. Other causes of Thyroid Nodules are:

Overgrowth of normal Thyroid Tissue – This really is also referred to as Thyroid Adenoma. It’s unclear to why this occurs but the thyroid adenoma can sometimes cause the thyroid to create hormones outdoors the pituitary glands regulations therefore generating much more thyroid hormones than required.

Thyroid Cyst – These fluid-filled cavities (cyst) outcomes from degenerating thyroid adenomas. They are typically benign but can sometimes contain malignant solid components.

Thyroid Cancer – The possibilities of nodules getting malignant are uncommon. The risk becomes higher though based on you as well as your family’s health-related history.

Broken Pituitary Gland – Issues using the pituitary gland may also trigger Thyroid Nodules.
Goiter is an additional thyroid issue which is either attributable to Graves Disease or Hashimoto’s Illness. The enlargement of the gland can be caused by either an excessive amount of hormone or lack of it. Other causes of goiter are as follows:

Iodine Deficiency – Lack of iodine in the body is really the primary result in of Goiter. It’s extremely important in the production of thyroid hormones. Goiter is brought on when the thyroid enlarges in an work to obtain much more iodine.

Multinodular Goiter – Strong or fluid-filled lumps known as nodules create in both sides from the thyroid. This leads to more than enlargement in the gland.

Solitary Thyroid Nodules – A single nodule develops in a single side from the thyroid gland. This also causes enlargement.

Thyroid Cancer – This is a significantly less frequent lump that develops in our thyroid gland. The cancer lump can also result inside the formation of Goiter.

Thyroiditis – Inflammation in the thyroid gland may also result in Goiter because of the swelling.
Pregnancy – A hormone made in the course of the initial tri-mester of pregnance (human chorionic gonadotrophin or HCG) can cause Goiter. The gland errors HCG for thyroid stimulating hormone (TSH) and enlarges in response to it.
As you are able to see, it really is nonetheless unclear as towards the real trigger of thyroid difficulties. All issues have a number of aspects to think about, however the real root cause have however to be identified (save for iodine deficiency). You may notice that a thyroid difficulty can lead to a number of a lot more thyroid issues. It is crucial to often have check-up with your medical doctor, especially in the event you feel one thing various or abnormal along with your thyroid gland.

Taking care in the difficulty early will assist lessen the problem and can save you funds.


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Thyroid

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The thyroid is really a tiny gland that lies inside the neck concerning the level of the Adam’s apple and weighs around a single ounce. It produces thyroid hormone and calcitonin. The parathyroid glands are extremely tiny and lie around the outside portion from the thyroid gland and secrete parathyroid hormone. We are going to be focusing on thyroid hormone.

The thyroid gland is stimulated to create thyroid hormone by thyroid-stimulating hormone (TSH) that is created within the pituitary gland situated inside the brain. The pituitary is controlled by the hypothalamus in the brain which monitors the level of circulating thyroid hormone. Iodine need to enter the thyroid gland through a transport program that’s repaired using the intake of vitamin C. There is certainly generally about 20-30 mg of iodine inside the physique and 75 percent of it really is stored in the thyroid. In addition to iodine, magnesium, zinc, copper, and vitamins B2, B3, and B6 are needed for thyroid hormone production.

The thyroid gland produces two thyroid hormones: T4 (thyroxine) and T3 (triiodothyronine). Ninety-five percent of thyroid hormone made is T4 and five percent is T3. T3 will be the active form of thyroid hormone which can be created because of 1 iodine getting cleaved from T4. T4 is inactive so the majority of thyroid hormone created is actually inactive. The numbers “3” and “4” indicate the number of iodines. This really is important in understanding optimal thyroid function. Each T4 and T3 are bound to proteins inside the blood till they reach your cells and grow to be unbound to work their magic on metabolism.

Most of the T4 is converted into T3 inside the liver. Around sixty % of the T4 is converted into T3, twenty % is converted into an inactive type of thyroid hormone recognized as reverse T3 (irreversible), and also the remaining twenty % is converted into T3S (T3 sulfate) and T3AC (triiodothyroacetic acid).

Reverse T3 may be problematic; although it really is inactive, it’s going to still bind to T3 receptors and block T3 from binding and functioning its magic on metabolism. As well a lot or also tiny cortisol that is created by the adrenal glands will improve circulating levels of reverse T3. This mechanism is because of suppressed liver detoxification and clearance of reverse T3 from excess cortisol production. Anxiety can not just cause indicators of hypothyroidism nevertheless it may also impair the liver’s ability to detoxify. Cortisol will also suppress TSH production resulting in low thyroid function. Immune program activation, high adrenaline, excess free of charge radicals, aging, fasting, stress, prolonged illness, and diabetes may also drive the inactivation of T3 to reverse T3.

T3 and reverse T3 may also be inactivated by conversion into a hormone identified as T2. Elevated insulin levels due to a diet program high in refined carbohydrates will also boost reverse T3 levels. Toxic metals including mercury, cadmium and lead may also improve reverse T3 production. T3S and T3AC are inactive until they are catalyzed by an enzyme within the GI tract identified as sulfatase. This enzyme is dependent on healthy gut bacteria. We are going to talk about within a later chapter the importance of a healthful digestive tract as it relates to twenty percent of active thyroid hormone.

Thyroid hormone’s main role is always to control metabolism (power production) inside the cell. Our cells contain tiny factories known as mitochondria that produce power from fat, sugar and protein. Thyroid hormone controls the function in the mitochondria which determines just how much energy is produced. Symptoms of low thyroid function are connected to a lower in energy production which includes:

Fatigue
Weight gain/inability to lose weight
Constipation
Dry/itchy skin
Dry brittle hair and nails
Depression
Headaches
Overly sensitive to cold
Cold/numb hands and feet
Muscle cramps
Depressed immune system-can’t recover from infections
Slow wound healing
Unrefreshing sleep
Digestive problems as a result of low stomach acid
Hair falls out
Water retention
Lateral third of eyebrow thinning
TSH

Conventional medicine relies mostly on the TSH or thyroid-stimulating hormone blood test to measure thyroid function. TSH is not a thyroid hormone. TSH is produced by the pituitary according to just how much thyroid hormone is circulating within the bloodstream. As thyroid hormone levels drop, TSH production will improve to stimulate the thyroid to make a lot more hormone. If thyroid hormone increases, then TSH production will lower because the thyroid is creating lots of hormone. The TSH alone just isn’t sufficient to assess thyroid function simply because it doesn’t take into consideration the conversion of thyroid hormone into its active type which happens in the liver, kidneys and lungs. The TSH test also does not take into account thyroid hormone receptor resistance. Thyroid hormone receptors can grow to be resistant to thyroid hormone as a result of thyroid-disrupting chemical exposure major to normal blood tests but improvement of low thyroid symptoms. Cortisol made throughout anxiety by the adrenal gland can also inhibit TSH production further throwing off the accuracy in the test. When the TSH is elevated, the traditional physician will prescribe synthetic T4 and this will typically decrease TSH into the “normal” range. This strategy will not take into account peripheral thyroid hormone conversion or receptor binding. In the event the body is compromised in its ability to activate thyroid hormone into T3, then taking T4 will outcome within a failure of treatment. When the adrenal glands are out of balance, then probably thyroid hormone function will also be out of balance. Additionally, if thyroid hormone receptors are desensitized, this approach will fail also.

You are going to discover that most health-related physicians usually do not invest much time reading the peer-reviewed healthcare literature which provides us with useful data on TSH levels. An excellent study was published by Obal and Krueger (2001)on sleep deprivation and thyroid hormone production. The researchers concluded: “When sleep deprivation is maintained for weeks, the plasma concentrations of T4 and especially T3 decline but TSH remains normal.”6 Do physicians ask you about your sleep patterns? Possibly this could be the purpose for the abnormal TSH. I’ve seen many individuals who also endure from insomnia and sleep problems and present with low thyroid symptoms and abnormal TSH levels. Does this imply they must have thyroid hormone dumped into their bodies? Unfortunately, this takes place to lots of people. I always take into account each patient’s sleep pattern and appropriate it as a part of our therapy strategy. Many occasions, sleep patterns are abnormal as a result of blood sugar and adrenal gland imbalances. Keep in mind, you’re not a lab test but a stunning, complicated getting where everything is connected as 1.

Testing & Diagnosis

Blood tests alone cannot usually adequately diagnose thyroid hormone imbalance. It really is estimated that about forty percent in the U.S. population suffers from some kind of thyroid imbalance as opposed to the current standard figure of ten %. This is as a result of the inadequacies from the TSH test. Furthermore to blood testing, I review a thorough case history and a variety of detailed health questionnaires and also perform a comprehensive physical examination for clues to thyroid hormone imbalance. Basal physique temperature testing is used by numerous practitioners to evaluate thyroid function but this does not solely indicate a thyroid imbalance. There are several other factors that can trigger a low basal physique temperature such as adrenal fatigue, leaky gut, impaired liver detoxification and malnutrition. I use the basal body temperature simply as one a lot more diagnostic tool to evaluate the overall picture of a patient. Another sign that may indicate low thyroid function is thinning of the lateral one-third in the eyebrow.

The following thyroid tests can provide more information about your thyroid. Use this as a guide when you get the results of your blood tests:

TSH (Thyrotropin) – Thyroid-stimulating hormone is made by the pituitary to stimulate the thyroid to make hormone. The ideal range is 1.8-3.0. Conventional medicine uses a much broader variety of 0.5-5.5. This variety misses numerous hypothyroid sufferers such as those with a TSH between 3.0-5.5.

Total Thyroxine (T4) – This test measures the quantity of T4 (thyroxine) that is both bound to protein and unbound.

Totally free Thyroxine Index – This is calculated by multiplying the TT4 by the T3 uptake. The outcome gives you the quantity of unbound T4 or Totally free T4.

Free of charge Thyroxine (Free of charge T4) – This measures the amount of unbound or totally free T4 which can be the most active type. Free T4 just isn’t affected by medications or other factors that affect protein bound thyroxine (TT4).

T3 Uptake – A measurement of the amount of available binding sites for free of charge T3 on thyroxine-binding proteins. Elevated testosterone will minimize the amount of binding sites and trigger a low T4 and high T3 uptake. Excess estrogen from hormone replacement or birth handle pills will increase binding sites and can result in high T4 and low T3 uptake.

Free of charge Triiodothyronine (Totally free T3) – This can be a measure of totally free T3 levels or unbound T3. This can be the best test if your natural physician wants to see the quantity of available active thyroid hormone inside the bloodstream.

Reverse T3 (rT3) – This is a measurement from the quantity of T3 that has been inactivated.

Thyroid Antibodies – Thyroid peroxidase, thyroid-stimulating immunoglobulin and antithyroglobulin elevations indicate Ipotiroidismo autoimmune thyroid disease such as Hashimoto’s or Graves’ disease. Thyroglobulin and calcitonin are mainly used in the diagnosis of more serious thyroid diseases such as cancer.

Prescription Medications

Prescription medications don’t take into account underlying physiological imbalances and may lead to dependence on the medication. The following drugs are prescribed by physicians to treat the thyroid:

Synthroid – Synthetic thyroxine (T4). Synthroid will be the most popular prescription drug for hypothyroidism. Synthroid is within the top 5 most commonly prescribed drugs inside the US. Synthroid can be converted incorrectly into inactive reverse T3 resulting in no symptom improvement. Synthroid depletes calcium for bones and may not provide improvement for sufferers who have compromised conversion pathways of T4 into T3 or any of the other imbalances described in this book.
Levoxyl – Synthetic thyroxine (T4).
Levothroid – Synthetic thyroxine (T4).
Levothyroxine – Synthetic thyroxine (T4).
Thyrolar – Synthetic T4 and T3.
Cytomel – Synthetic T3. Many side effects which includes hyperthyroid symptoms.

Armour Thyroid, Nature Thyroid, Westhroid – Natural thyroid hormone from desiccated pig thyroid tissue. Contains roughly 38 micrograms/grain of T4 and 9 micrograms of T3/grain too as other cofactors for thyroid hormone production. Nature Thyroid is a better choice than Armour since it will not include corn and other binders.

Several alternative-minded medical doctors prescribe Armour and other natural desiccated pig thyroid tissue. This is a better option in some cases than merely prescribing synthetic T4 (Synthroid) simply because these natural agents also contain T3. The problem with Armour is that it contains corn and other fillers which could be a problem for those with specific sensitivities. Nature Thyroid is the best choice because it doesn’t include corn or fillers. But the author will not agree with this treatment method because although it’s a better option, it still doesn’t take into account the underlying causes of why the thyroid is out of balance within the first place. These natural prescriptions nonetheless only replace thyroid hormone and require dependence around the doctor for continued prescriptions and office visits. I’ve seen several, many sufferers who are on such natural prescriptions who still have many symptoms and have been taking the prescription for a long period of time. Even if someone responds to a prescription such as Armour thyroid, she must be rigorously evaluated for underlying physiological imbalances.

Another issue with such remedy methods is suppression of hypothalamic-pituitary-thyroid feedback mechanisms. Whenever you take a hormone that is produced inside the body, this tells the brain that it no longer needs to stimulate hormone production simply because it’s constantly being ingested. When male bodybuilders take testosterone, their testicles shrink since there’s no longer a need for them to produce testosterone. Taking thyroid hormone for long periods of time will suppress natural production which may or may not return after discontinuing the medication. It’s strongly encouraged that you do every thing possible to normalize thyroid function before going on medication of any kind. Americans typically want a quick fix, a magic pill that will instantly give relief. Many people get this instant relief from medication but the long-term effects of dependency and suppression of natural hormone production may not be worth it. Patients who have had their thyroid removed or partially removed may require prescription thyroid hormone. In the event the gland isn’t present then thyroid hormone must be replaced. In this case, prescriptions such as Armour and Nature Thyroid are the better choice.

Conversion of T4 into T3

T3 is significantly more active than T4 and is responsible for most of the actions of thyroid hormone on the cell. Some folks cannot convert T4 into T3 as efficiently as others. Furthermore, there are several factors that could possibly be inhibiting this process.

Selenium, antioxidants, iron, magnesium, zinc, vitamin A, vitamin B6 and B12 deficiencies can lead to poor conversion. The medications listed above affect thyroid hormone conversion also as production and receptor binding. As people get older, they lose their ability to convert thyroid hormone which may be due to decreased vitamin and mineral absorption. This is due to a loss of intestinal barrier function where all of your nutrition is absorbed. This barrier loses its function as we age so supplementation is absolutely necessary. Excess estrogen from xenoestrogens inside the environment, birth control pills and hormone replacement can lead to low thyroid symptoms. Estrogen increases the protein that binds to thyroid hormone leaving excess thyroid hormone bound to protein that is inactive till it becomes unbound. Cortisol created by the adrenal gland is really a major factor in converting thyroid hormone. Too a lot cortisol can inhibit the activation of thyroid hormone and also little cortisol yields the same result. Exhausted adrenals will cause low thyroid symptoms due to the lack of cortisol production. Insulin is a hormone released by the pancreas to handle blood sugar elevations after consumption of carbohydrates and can inhibit hormone conversion too. Soy products have been shown to inhibit the conversion of thyroid hormone. This only goes for soy products that are non-fermented. Fermented soy products such as miso and tempeh are okay.

Vitamin C has been shown to enhance the conversion of thyroid hormone. Radiation, chemotherapy, growth hormone deficiency, and cigarette smoke have also been shown to decrease thyroid hormone conversion.


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